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ДНК-проект: общие вопросы

Вопрос

http://vivovoco.nns.ru/VV/JOURNAL/VRAN/03_...7/ETHNOGENE.HTM

Из рис.4 видно, что в целом европеоидные линии встречаются у всех без исключения тюрков и в целом доминируют над монголоидными. Мне кажется это достаточный факт для того, чтобы признать, что европеидность тюркам была присуща изначально и вовсе не является молодым субстратом.

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02.07.2018 в 12:05, кылышбай сказал:

из ваших?  уфулл с возрастом тмсра 1600лет

https://yfull.com/tree/N-Y16323/

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МолГен -всё ?

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3 минуты назад, Samtat сказал:

МолГен -всё ?

работает уже , утром не фурычил 

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Цитата

https://www.nature.com/articles/s41431-018-0211-6

Paternal origin of Paleo-Indians in Siberia: insights from Y-chromosome sequences

    Lan-Hai Wei, Ling-Xiang Wang, Shao-Qing Wen, Shi Yan, Rebekah Canada, Vladimir Gurianov, Yun-Zhi Huang, Swapan Mallick, Alessandro Biondo, Amy O’Leary, Chuan-Chao Wang, Yan Lu, Chao Zhang, Li Jin, Shuhua Xu & Hui Li 

European Journal of Human Genetics (2018) | Download Citation

Abstract

The expansion of modern humans to the American continent after the Last Glacial Maximum led the way to the present-day distribution of American aborigines. Recent advances in autosomal DNA research and expanded testing of mtDNA lineages has provided a clearer picture of the number and timing of founding lineages. However, both autosomal DNA and mtDNA research have provided unresolved competing theories between the short-term and the long-term models of the Beringian standstill hypothesis. Further, the source of founding paternal lineages of American aborigines and their relationship with ancient Siberia populations remains ambiguous. In this study, we reanalyzed a 7.0 Mbp region of 132 paternal Y-chromosome sequences, including 39 newly reported ones, of male samples from American aborigines and Eurasian populations. Among Eurasian samples, we identified Y-chromosome branches that are most closely related to known American aborigine founding lineages, that is, Q1-L804 links to Q1-M3, Q1-L330 links to Q1-Z780, Q1-M120 links to Q1-B143, and C2-F1756 links to C2-P39. The revised phylogenetic tree and age estimates indicate a narrow timeframe (~15.3–14.3 kya) for the upper time limit of human entry to the American continent. Our analysis suggests that the in situ differentiation of Q-M242 in Central Eurasia and South Siberia region gave rise to numerous sub-lineages older than 15.3 kya, and the founding of Paleo-Indian paternal lineages is part of the great Q1-L53 diffusion throughout the Eurasia after the Last Glacial Maximum. The results of our study will assist in future studies of the history of modern populations in Eurasia and the Americas.

 

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New FGC publication with collaborators: 
Leon Kull (FGC team member) and Greg Magoon (Full Genomes bioinformatics consultant and employee at Aerodyne) worked on the paper along with other collaborators:

Haplogroup J-Z640 - Genetic Insight into the Levantine Bronze Age

Michael Waas1,2, Doron Yacobi3, Leon Kull 4, Vadim Urasin5, Gregory R. Magoon 6, Wim Penninx7, Adam Brown2, Ines Nogueiro8,9

1.Jewish History, University of Haifa, Haifa, Israel , 2.Avotaynu Dna, Avotaynu Dna, Teaneck, Nj, United States , 3.Independent, Independent, Tel Aviv, Israel , 4.Full Genomes Corp., Full Genomes Corp., Rockville, Md, United States , 5.Researcher, Y full.com, Moscow, Russian Federation , 6.Aerodyne Research, Inc., Aerodyne Research, Inc., Billerica, Ma, United States , 7.Independent, Independent Genetic Genealogy Researcher, Delft, Netherlands , 8.Institute of Molecular Pathology and Immunology of the University of Porto (Ipatimup), Universidade Do Porto, Porto, Portugal , 9.Instituto De Investigação E Inovação Em Saúde, Universidade Do Porto, Porto, Portugal

Haplogroup J-Z640 is a Y chromosome lineage found most notably, in several minority groups within the Near East that have undergone tremendous selection pressure in both the recent and distant past such as the Samaritans, Druze, Armenians and Jews. The evolution of J-Z640 and the common origin of the diverse ethno-religious groups within it has never been studied. We compiled a STR (short tandem repeat) and SNP (single nucleotide polymorphism) dataset of 130 known or predicted J-Z640 samples among the customers of FamilyTreeDNA and FullGenomes Corporation, as well as publicly available samples. Amongst these, we analyzed the results of 41 samples that had undergone Next-Generation Sequencing and 32 samples that had undergone SNP testing using Sanger Sequencing. From this data, we constructed a J-Z640 phylogenetic tree. Our data revealed that J-Z640 originated during the Middle Bronze Age, most likely in the Levant. During the period 2100 BCE - 1200 BCE the haplogroup rapidly expanded with multiple ancient branches surviving to the present, evidencing population growth. Further population expansion, and contraction, were also observed in later periods. Based on its geographic dispersal and age of the haplogroup and its subclades, the founder population most likely belonged to Canaanites found in the Levant. Following the collapse of the late Bronze age system (1200-1177 BCE), there followed a period of ‘differentiation by culture’, with many of the ancient branches surviving to the present separated along ethno-religious lines.

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Где это опубликовано?

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Перепостил с Фэйсбука

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http://xn--c1acc6aafa1c.xn--p1ai/?page_id=30293

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Цитата

http://www.ivpp.cas.cn/cbw/rlxxb/xbwzxz/201805/P020180515379362334965.pdf

Citation: Liu SH, N, Yilihamu, R Bake,et al. A study of genetic diversity of three isolated populations in Xinjiang using Y-SNP[J]. Acta Anthropologica Sinica, 2018, 37(1): 146-156

DOI: 10.16359/j.cnki.cn11-1963/q.2017.0067

A  study  of  genetic  diversity  of  three  isolated  populations in Xinjiang using Y-SNP

LIU Shuhu, NIZAM Yilihamu, RABIYAMU Bake, ABDUKERAM Bupatima, DOLKUN Matyusup

College of the Life Sciences and Technology, Xinjiang University, Urumqi 830046

Abstract:  The Keriyan, Lopnur and Dolan peoples are isolated populations with sparse numbers living  in  the  western  border  desert  of  our  country.  By  sequencing  and  typing  the  complete  Y-chromosome of 179 individuals in these three isolated populations, all mutations and SNPs in the Y-chromosome and their corresponding haplotypes were obtained. Types and frequencies of each  haplotype  were  analyzed  to  investigate  genetic  diversity  and  genetic  structure  in  the  three  isolated populations. The results showed that 12 haplogroups were detected in the Keriyan with high frequencies of the J2a1b1 (25.64%), R1a1a1b2a (20.51%), R2a (17.95%) and R1a1a1b2a2 (15.38%) groups. Sixteen haplogroups were noted in the Lopnur with the following frequencies: J2a1  (43.75%),  J2a2  (14.06%),  R2  (9.38%)  and  L1c  (7.81%).  Forty  haplogroups  were  found  in  the  Dolan,  noting  the  following  frequencies:  R1b1a1a1  (9.21%),  R1a1a1b2a1a  (7.89%),  R1a1a1b2a2b (6.58%) and C3c1 (6.58%). These data show that these three isolated populations have  a  closer  genetic  relationship  with  the  Uygur,  Mongolian  and  Sala  peoples.  In  particular,  there  are  no  significant  differences  in  haplotype  and  frequency  between  the  three  isolated  populations and Uygur (f=0.833, p=0.367). In addition, the genetic haplotypes and frequencies in the three isolated populations showed marked Eurasian mixing illustrating typical characteristics of Central Asian populations.

 

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